The key setup most people use are

w=move forward
a=strafe left
s=move backward
d=strafe right
space=jump
ctrl=crouch
rightmouse=fire
leftmouse=altfire
middlemouse=selectbestweapon

The translocator requires LOTS of practice. When you hit fire and the trans goes up, hit altfire to trans there and hit fire right away. 

As far as conflictins shit on your sytem, I have no idea?

Hope that helps.